39. Brafman, D.A., Chang, C.W., Fernandez, A., Willert, K.A., Varghese, S.*, and Chien, S. "Long term human pluripotent stem cell self-renewal on synthetic polymer surfaces. " Biomaterials, 31:9135-9144, (2010) (*co-corresponding author) Link; Pubmed Link

38. Phadke, A., Zhang, C., Hwang, Y., Vecchio, K., and Varghese, S. "Templated Mineralization of Synthetic Hydrogels for Bone-Like Composite Materials: Role of Matrix Hydrophobicity". Biomacromolecules, 11:2060-2068, (2010). Link; Pubmed Link

37. Chang, C.W., Spreeuwel, A., Zhang, C., and Varghese, S. "PEG/Clay Nanocomposite Hydrogel: A Mechanically Robust Tissue Engineering Scaffold" Soft Matter, 6, 5157-51654 (2010). Link

36. Hwang, Y.S., Sangaj, N., and Varghese, S. "Interconnected Macroporous Pol(ethyleneglycol)(PEG) Cryogels as A Cell Scaffold for Cartilage Tissue Engineering" Tissue Engineering Part A, 16, 3033-3041 (2010). Link; Pubmed Link

35. Phadke, A. and Varghese, S. "Synthetic Biomaterials and stem cells for connective tissue engineering." Book Chapter in CRC Handbook of Biomedical Engineering.

34. Phadke, A., Chang, C., and Varghese, S. "Functional Biomaterials for Controlling Stem Cell Differentiation." Book Chapter in Stud Mechanobiol Tissue Eng Mater 2:19-44 (2010) Link

33. Sangaj, N., and Varghese, S. "Controlling stem cells with materials." Book Chapter in “Biomaterials for Tissue Engineering: A Review of the Past and Future Trends”

32. Varghese, S.*, Hwang, N.S., Ferran, A., Hillel, A., Theprungsirikul, P., Canver, C.A., Zhang, Z., Gearhart, J., and Elisseeff, J.H.* "Engineering Musculoskeletal Tissue with Human Embryonic Germ Cell Derivatives" Stem Cells , 28, 765-774 (2010). (*co-corresponding author) Link; Pubmed Link

31. Brammer, K.S., Oh, S., Frandsen, C.J., Varghese, S., and Jin, S. "Nanotube surface triggers increased chondrocyte extracellular matrix production" Mater. Sci. Eng. C (2010). Link

30. Hwang, Y., Zhang, C., and Varghese, S. "Poly(ethylene glycol) cryogels as potential cell scaffolds: effect of polymerization conditions on cryogel microstructure and properties" J. Mater. Chem., 20, 345-351 (2009). Link

29. Lee, H.J., Yu, C., Chanskul, T., Hwang, N., Varghese, S., and Elisseeff, J.H. "Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-mediated microenvironment," Tissue Eng Part A 14(11):1843-51 (2008) Link; Pubmed Link

28. Zhang, C., Aung, A., Liao, L., and Varghese, S. "A novel single precursor-based biodegradable hydrogel with enhanced mechanical properties" Soft Matter, 5, 3831-3834 (2009). Link

27. Hillel, A.T., Varghese, S., Petsche, J., Shamblott, M.J., and Elisseeff, J.H. "Embryonic Germ Cells Are Capable of Adipogenic Differentiation In Vitro and In Vivo" Tissue Eng. Part A, 15, 479-486 (2009). Link; Pubmed Link

26. Hwang, N.S., Varghese, S., and Elisseeff, J.H. "Derivation of Chondrogenically-Committed Cells from Human Embryonic Cells for Cartilage Tissue Regeneration" PLoS One, 3: e2498 (2008). Link; Pubmed Link

25. Hwang, N.S., Zhang, C., Hwang, Y., and Varghese, S., "Mesenchymal Stem Cell Differentiation, and Their Role in Regenerative Medicine" Sys. Biol. Med., 1, 97-106 (2009). Link; Pubmed Link

24. Hwang, N.S., Varghese, S., Lee, J., Zhang, Z., Ye, Z. Bae, J., Cheng, L. and Elisseeff, J. H. "In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells" PNAS, 105, 20641-20646 (2008). Link; Pubmed Link

23. Lee, H.J., Chansakul, T., Varghese, S., Hwang, N.S., Elisseeff, J.H. "The effect of immobilized HA binding peptide on cartilage engineering in hydrogels". (submitted)

22. Lee, H.J., Yu, C., Chansakul, T., Varghese, S., Hwang, N.S., Elisseeff, J.H. "Enhanced Chondrogenic Differentiation of Embryonic Stem Cells by Co-Culture with Hepatic Cells," Stem Cells Dev., 17, 555-563 (2008). Link; Pubmed Link

21. Varghese, S., Hwang, N.S., Canver, C.A., Lin, D., Theprungsirikul, P., and Elisseeff, J.H. "Chondroitin sulfate based hydrogel niche for chondrogenic differentiation of mesenchymal stem cells" Matrix Biology, 27, 12-21 (2008). Link; Pubmed Link

20. Hwang, N.S., Varghese, S., and Elisseeff, J.H. "Controlled differentiation of stem cells" Adv. Drug Deliver. Rev., 60, 199-214 (2008). Link; Pubmed Link

19. Lee, H.J., Yu, C., Chansakul, T., Hwang, N.s., Varghese, S., Yu, S.M., and Elisseeff, J. H. "Enhanced Chondrogenesis of Mesenchymal Stem Cells in Collagen Mimetic Peptide-Mediated Microenvironment" Tissue Eng., 14, 1843-1851 (2008). Link; Pubmed Link

18. Wang, D.A., Varghese, S., Sharma, B., Strehin, I., Fermanian, S., Gorham, J., Fairbrother, D.H., Cascio, B., Gurken, I., and Elisseeff, J.H. "Multifunctional chondroitin sulphate for cartilage tissue-biomaterial integration" Nature Materials, 6, 385-392 (2007). Link; Pubmed Link

17. Hwang, N.S., Varghese, S., Lee, H.J., Theprungsirikul, P., Canver, C. A., Sharma, B., and Elisseeff, J. H. "Response of zonal chondrocytes to extracellular matrix hydrogels" FEBS Lett., 581, 4172-4178 (2007). Link; Pubmed Link

16. Lee, H.J., Varghese, S., Hwang, N., and Elisseeff, J.H. "Nanoengineered Hydrogels for Cartilage Tissue Engineering" in Micro and Nanoengineering of the Cell Microenvironment Technologies and Applications, Artech House Publishing Inc.

15. Hwang, N.S., Varghese, S., Puleo, C., Zhang, Z., and Elisseeff, J.H. "Morphogenetic Signals from Chondrocytes Promote Chondrogenic and Osteogenic Differentiation of Mesenchymal Stem Cells" J. Cell. Physiol., 212, 281-284 (2007). Link; Pubmed Link

14. Varghese, S., Theprungsirikul, P., Sahani, S., Hwang, N.S., Yarema, K.J., and Elisseeff, J.H. "Glucosamine modulates chondrocyte proliferation, matrix synthesis and gene expression" OsteoArth. Cartilage, 15, 59-68 (2007). Link; Pubmed Link

13. Hwang, N.S., Varghese, S., and Elisseeff, J.H. "Cartilage Tissue Engineering: Directing Differentiation of Embryonic Stem Cells in Three-Dimensional Hydrogel Cultures" Methods Mol. Biol. (Stem Cell Assays), 407, 351-373 (2007). Link; Pubmed Link

12. Varghese, S., Theprungsirikul, P., Ferran, A., Hwang, N.S., Canver, A., and Elisseeff, J.H "Chondrogenic differentiation of human embryonic germ cell derived cells in hydrogels" IEEE EMB Eng Med and Biol, 1, 2643-2646 (2006). Link; Pubmed Link

11. Varghese, S., and Elisseeff, J.H. "Hydrogels for Musculoskeletal Tissue Engineering" Adv. Polym. Sci., 203, 95-144 (2006). Link

10. Varghese, S.*, Hwang, N.S.*, Theprungsirikul, P., Canver, A., and Elisseeff, J.H. "Enhanced chondrogenic differentiation of murine embryonic stem cells in hydrogels with glucosamine" Biomaterials, 27, 6015-6023 (2006). [*authors contributed equally]Link; Pubmed Link

9. Elisseeff, J.H., Ferran, A., Hwang, S., Varghese, S., and Zhang, Z. "The Role of Biomaterials in Stem Cell Differentiation: Applications in the Musculoskeletal System" Stem Cells Dev., 15, 295-303 (2006). Link; Pubmed Link

8. Hwang, N.S., Varghese, S., Zhang, Z., and Elisseeff, J.H. "Chondrogenic Differentiation of Human Embryonic Stem Cell-Derived cells in Arginine-Glycine-Aspartate-Modified Hydrogels" Tissue Eng., 12, 2695-2706 (2006). Link; Pubmed Link

7. Varghese, S., Lele, A.K., and Mashelkar, R.A. "Metal-Ion-Mediated Healing of Gels" J. Polym. Sci. Part A: Polym. Chem., 44, 666 (2006). Link