85. Shih Y-R, Kang H, Rao V, Chiu Y-R, Kwon SK, Varghese S*. “In vivo engineering of bone tissues with hematopoietic functions and mixed chimerism” PNAS, 114, 5419, 2017. San Diego Union Tribune; TheScientist; New Atlas; CIRM; MedicalDesign&Outsourcing; Outlook ; KPBS; Fururism; Gizmodo; NewScientist; STAT; UCSD; NewsIndia; IndianExpress; TheHindu; Link

84. Aung A, Theprungsirikul J, Lim HL, Varghese S*. “Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform” Lab on a Chip, 2016 (in press). Link

83. Seale N, Varghese S. “Biomaterials for pluripotent stem cell engineering: from fate determination to vascularization” J Mater. Chem. B, 2016 (in press). Link

82. Kang H, Shih YRV, Nakasaki M, Kabra H, Varghese S*. “Small molecule-driven direct conversion of human pluripotent stem cells into functional osteoblasts” Science Advances, 2016 (in press). Nature Highlight; UC highlight; Link

81. Gonzalez-Diaz EC, Varghese S*. “Hydrogels as Extracellular Matrix Analogs” MDPI, 2016 (in press). Link

80. Mo AH, Landon PB, Gornez KS, Kang H, Lee J, Zhang C, Janetanakit W, Sant V, Lu T, Colburn DA, Akkiraju S, Dossou S, Cao Y, Lee KF, Varghese S, Gennadi G, and Lal R. “Magnetically-responsive silica-gold nanobowls for targeted delivery and SERS-based sensing” Nanoscale, 8: 11840-11850, 2016. Link

79. Nakasaki M, Hwang Y, Xie Y, Kataria S, Gund R, Hajam EY, Samuel R, George R, Danda D, Paul MJ, Nakamura T, Shen Z, Briggs S, Varghese S*, Jamora C*. “The matrix protein Fibulin-5 lies at the interface of tissue stiffness and inflammation in fibrosis” Nat Comms 6 (2015). *co-corresponding authors. Link; Pubmed; Scleroderma; Health News; ZeeNews; Indiatimes; Bioeng highlight ; JSoE news ; UCSD news

78. Aung A, Bhullar IS, Theprungsirikul J, Davey SK, Lim HL, Chiu YJ, Ma X, Dewan S, Lo YH, McCulloch A, Varghese S “3D cardiac µtissues within a microfluidic device with real-time contractile stress readout” Lab Chip. Jan 7;16(1):153-62. (2016) Link

77. Davey SK*, Aung A*, Agrawal G, Lim HL, Kar M and Varghese S. “Embedded 3D photo-patterning of hydrogels with diverse and complex architectures for tissue engineering and disease models” Tissue Eng Part C Methods. Nov;21(11):1188-96 (2015); Cover ; Link

76. Kar M, Shih Y-RV, Velez DO, Cabrales P and Varghese S “Poly(ethylene glycol) hydrogels with cell cleavable groups for autonomous cell delivery” Biomaterials. Jan;77:186-97 (2016)

75. Rao V, Shih Y-RV, Kang H, Kabra H, and Varghese S. “Adenosine signaling mediates osteogenic differentiation of human embryonic stem cells on mineralized matrices” Front. Bioeng. Biotechnol. Nov 10;3:185. (2015; Invited) Link

74. Wen C, Kang H, Shih Y-RV, Hwang Y, and Varghese S. “In vivo comparison of biomineralized scaffold-directed osteogenic differentiation of human embryonic and mesenchymal stem cells” Drug Del Trans Res. Apr;6(2):121-31 (2016) Link ; Pubmed Link

73. Shih Y-RV, Phadke A, Yamaguchi T, Kang H, Inoue N, Masuda K and Varghese S. “Synthetic bone mimetic matrix-mediated in situ bone tissue formation through host cell recruitment” Acta Biomaterialia. Jun;19:1-9 (2015) Link ; Pubmed Link

72. Kang H, Shih Y-RV, Varghese S. “Biomineralized matrices dominate soluble cues to direct osteogenic differentiation of human mesenchymal stem cells through adenosine signaling” Biomacromolecules, 2015, 16 (3), pp 1050–1061(2015) Link ; Pubmed Link ; Mesenchymal Stem Cell News Highlight ;

71. Kabra H*, Hwang YS*, Lim HL, Kar M, Arya G and Varghese S. “Biomimetic Material-Assisted Delivery of Human Embryonic Stem Cell Derivatives for Enhanced In Vivo Survival and Engraftment” ACS Biomater. Sci. Eng., 2015, 1 (1), pp 7–12 (2014) Link * denotes equal author contribution

70. Aung A, Seo T, Lu S, Wang Y, Jamora C, del Alamo JC, and Varghese S. “3D Traction stresses activate protease-dependent invasion of cancer cells” Biophys. J 107(11):2528-2537 (2014) Link ; Biophys Highlight ; Pubmed Link

69. Kang J, Park HM, Kim YW, Kim YH, Varghese S, Seok HK ,Kim YG and Kim SH. "Control of mesenchymal stem cell phenotype and differentiation depending on cell adhesion mechanism" ECM 28:387-403 (2014) Link ; Pubmed Link

68. Kim HD, Heo JS, Hwang YS, Kwak S-Y, Park OK, Kim HB, Varghese S, and Hwang NS. "Extracellular-Matrix-Based and Arg-Gly-Asp–Modified Photopolymerizing Hydrogels for Cartilage Tissue Engineering" Tissue Engineering Part A (2014) Link ; Pubmed Link

67. Hwang YS, Suk S, Shih Y-RV, Kar M, Seo T, Du B, Xie Y, Li Z, and Varghese S. “WNT3A promotes myogenesis of human embryonic stem cells and enhances in vivo engraftment” Sci. Rep 4:5916 (2014) Link ; Pubmed Link

66. Kang H, Wen C, Hwang YS, Kan, Shih Y-RV, Kar M, Seo SW, and Varghese S. “Biomineralized matrix-assisted osteogenic differentiation of human embryonic stem cells” J. Mater. Chem. B 2(34):5676-5688 (2014) Link ; Pubmed Link

65. Kang H, Shih Y-RV, Hwang YS, Wen C, Rao V, Seo T, and Varghese S. “Mineralized gelatin methacrylate-based matrices induce osteogenic differentiation of human induced pluripotent stem cells” Acta Biomaterialia (in press) Link ; Pubmed Link

64. Shih Y-RV, Hwang YS, Phadke A, Kang H, Hwang NS, Caro EJ, Nguyen S, Siu M, Theodorakis EA, Gianneschi NC, Vecchio KS, Chien S, Lee OK and Varghese S. “Calcium phosphate-bearing matrices induce osteogenic differentiation of stem cells through adenosine signaling” PNAS 111(3): 990-995 (2014) Link; UCSD; ECM news; CIRM news; Science Blog; Pubmed Link

63. Caro-Diaz EJE, Aung A, Xu J, Varghese S and Theodorakis EA. “Fusarisetins: structure–function studies on a novel class of cell migration inhibitors” Org. Chem. Front (in press) Link ; Pubmed Link

62. Lim HL, Hwang YS, Kar M and Varghese S. “Smart hydrogels as functional biomimetic systems” Biomater. Sci. "Emerging Investigators" themed issue, 2(5):603-618 (2014) Link Downloads

61. Hwang YS, Suk S, Lin S, Tierney M, Du B, Seo T, Mitchell A, Sacco A, and Varghese S. “Directed In Vitro Myogenesis of Human Embryonic Stem Cells and Their In Vivo Engraftment” PLoS ONE 8(8):e72023 Link ; Pubmed Link

60. Castro-Cesena AB, Novitskaya EE, Phadke A, Varghese S, and McKittrick J. “Isolation of Collagen from Cortical Bovine Bone for Prepartion of Porous Collagen Sponges” Mechanics of Biological Systems an Materials 8: 73-28 Link

59. Hwang NS, Varghese S, Lee HJ, Zhang Z, Elisseeff J. “Biomaterials Directed In Vivo Osteogenic Differentiation of Mesenchymal Cells Derived from Human Embryonic Stem Cells”. Tissue Eng Part A. 19(15-16):1723-32 (2013) Link ; Pubmed Link

58. Phadke A, Hwang Y, Kim SH, Kim SH, Yamaguchi T, Masuda K, Varghese S. "Effect of Scaffold Microarchitecture on Osteogenic Differentiation of Human Mesenchymal Stem Cells" European Cells and Materials. ECM 25:114-129 (2013) Link ; Pubmed Link

57. Chang CW, Hwang Y, Brafman D, Hagan T, Phung C, Varghese S. "Engineering Cell-Material Interfaces for Long-term Expansion of Pluripotent Stem Cells." Biomaterials S0142-9612(12):1141-1146 (2012) Link; ECM news ; Pubmed Link

56. Phadke, A., Zhang, C., Arman, B., Hsu, C.H., Mashelkar, R.A., Lele, A.K., Tauber, M.J., Arya, G., and Varghese, S., "Rapid Self-Healing Hydrogel". Proceedings of the National Academy of Sciences (USA), in press, PNAS 109(12):4383-4388 (2012) Link; PNAS Highlight; PNAS Cover Highlight; UCSD; Research Expo; Pulse; MSNBC; Scientific American; Telegraph; GIT Europe; BPoD Display; ASME; Chemistry Views; Biopolymers Highlights; Youtube ; Pubmed Link

55. Varghese, S., Jamora, C. "Hydrogels: a versatile tool with a myriad of biomedical and research applications in the skin" Expert Reviews of Dermatology. 7(4) 315-317. (2012) Link

54. Phadke, A., Shih, YR., and Varghese, S. "Mineralized Synthetic Matrices as an Instructive Microenvironment for Osteogenic Differentiation of Human Mesenchymal Stem Cells". Macromol. BioSci. 12(8):1022-1032 (2012). Link ; Pubmed Link

53. Nguyen QT., Hwang Y., Chen AC., Varghese S., Sah RL. "Cartilage-Like Mechanical Properties of Poly(Ethylene Glycol)-Diacrylate Hydrogels" Biomaterials. 33(28):6682-90 (2012). Link ; Pubmed Link

52. Soman, P., Lee, J.W., Phadke, A., Varghese, S., and Chen S . "Spatial tuning of negative and positive Poisson's ratio in a multi-layer scaffold". Acta Biomaterialia. in press (2012). Link ; Pubmed Link

51. Soman, P., Fozdar, D.Y.,Lee, J.W., Phadke, A., Varghese, S., and Chen S "A Three-dimensional Polymer Scaffolding Material Exhibiting a Zero Poisson's Ratio". Soft Matter. 8:4946-4951(2012). Link ; Pubmed Link

50. Ayala, R., Zhang, C., Yang, D., Aung, A., Hwang, Y.S., Shroff, SS., Arce, F.T., Lal R., Arya, G., and Varghese, S., "Engineering the cell-material interface for controlling stem cell adhesion, migration, and differentiation". Biomaterials, 32:3700-3711, (2011) Link ; Pubmed Link

49. Varghese, S.,and Engler, A. "Musculoskeletal Cell Mechanics". Chapter in Orthopaedic Biomechanics book published by CRC Taylor and Francis. Link

48. Zhang, C., Sangaj, N., Hwang, Y.S., Phadke, A., Chang, C-W.,and Varghese, S., "Oligo(trimethylene carbonate)-poly(ethylene glycol)- oligo(trimethylene carbonate) triblock based hydrogels for cartilage tissue engineering ". Acta Biomaterials, 7:3362-3369 (2011) Link ; Pubmed Link

47. Hwang, Y.S., Phadke, A., and Varghese, S., "Engineered Microenvironments for Self-Renewal and Musculoskeletal Differentiation of Stem Cells". Future Medicine; Regenerative Medicine 6(4):505-524 (2011) Link ; Pubmed Link

46. Hwang, N.S., Varghese, S., Li, H., and Elisseeff, J., "Regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells in PEG-ECM hydrogels". Cell and Tissue Research 344(3):499-509 Link ; Pubmed Link

45. Lim, H.L., Chuang, J.C., Tran, T., Aung, A., Arya, G., and Varghese, S., "Dynamic Electromechanical Hydrogel Matrices for Stem Cell Culture". Advanced Functional Materials, 21:55-63, (2011) Link; UCSD; Materials Views ; Pubmed Link

44. Sangaj, N., Kyriakakis, P., Yang, D.,Chang, C.W., Arya, G., and Varghese, S., "Heparin mimicking polymer promotes myogenic differentiation of muscle progenitor cells". Biomacromolecules, 11:3294-3300, (2010). Link ; Pubmed Link

43. Neiman, V., and Varghese, S., "Synthetic Bio-actuators and Their Applications in Biomedicine". Smart Structures and Systems Journal (on Bioinspired Engineering and Interfaces) 7:185-198, (2011) Link

42. Lin SC., Sangaj N., Razafiarison T., Zhang C., Varghese S., "Influence of physical properties of biomaterials on cellular behavior". Pharmaceutical Research 28(6):1422-1430 (2011) Link ; Pubmed Link

41. Gillies, A.R., Smith, L.R., Lieber, R.L., and Varghese, S. "Method for decellularizing skeletal muscle without detergents or proteolytic enzymes". Tissue Engineering 17:383-389. (2011) Link ; Pubmed Link

40. Aung, A.*, Gupta, G*., Ghassemian, M., and Varghese, S. "Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells". Arthritis & Rheumatism, 63:148-158, (2011). Link ; Pubmed Link * denotes equal contribution